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Hirohisa Takano Selected Research

Organic Chemicals (Chemicals, Organic)

7/2017Environmental pollution and allergies.
12/2016Differences in allergic inflammatory responses in murine lungs: comparison of PM2.5 and coarse PM collected during the hazy events in a Chinese city.
4/2016Differences in allergic inflammatory responses between urban PM2.5 and fine particle derived from desert-dust in murine lungs.
10/2014Aggravation of ovalbumin-induced murine asthma by co-exposure to desert-dust and organic chemicals: an animal model study.
1/2013Organic chemicals in diesel exhaust particles enhance picryl chloride-induced atopic dermatitis in NC/Nga mice.
3/2007Components of diesel exhaust particles diversely enhance a variety of respiratory diseases related to infection or allergy: extracted organic chemicals and the residual particles after extraction differently affect respiratory diseases.
1/2007Effects of components derived from diesel exhaust particles on lung physiology related to antigen.
12/2006Effects of organic chemicals derived from ambient particulate matter on lung inflammation related to lipopolysaccharide.
11/2004Components of diesel exhaust particles differentially affect lung expression of cyclooxygenase-2 related to bacterial endotoxin.

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Hirohisa Takano Research Topics

Disease

69Inflammation (Inflammations)
12/2021 - 01/2002
39Pneumonia (Pneumonitis)
12/2021 - 05/2002
38Asthma (Bronchial Asthma)
01/2022 - 01/2002
17Eosinophilia
01/2017 - 01/2008
13Acute Lung Injury
04/2010 - 12/2002
12Lung Injury
11/2013 - 04/2002
10Respiratory Tract Diseases (Respiratory Tract Disease)
01/2022 - 04/2002
10Atopic Dermatitis (Atopic Eczema)
12/2021 - 08/2006
10Hypersensitivity (Allergy)
10/2021 - 11/2005
7Body Weight (Weight, Body)
01/2019 - 04/2004
6Pancreatitis
04/2010 - 03/2005
6Shock
04/2010 - 03/2005
6Disseminated Intravascular Coagulation
04/2010 - 03/2005
5Infections
01/2021 - 10/2004
5Obesity
01/2019 - 10/2003
5Respiratory Hypersensitivity
01/2019 - 12/2002
5Lung Diseases (Lung Disease)
02/2014 - 04/2003
4Allergic Rhinitis
11/2018 - 09/2007
4Edema (Dropsy)
02/2018 - 05/2002
4Hemorrhage
01/2013 - 05/2002
4Arthritis (Polyarthritis)
01/2007 - 08/2003
3Hyperplasia
08/2019 - 08/2007
3Peritonitis
02/2013 - 09/2003
3Pulmonary Emphysema
11/2010 - 03/2010
3Pulmonary Edema
09/2006 - 12/2002
2COVID-19
01/2021 - 12/2020
2Disease Progression
01/2020 - 03/2010
2Chronic Obstructive Pulmonary Disease (COPD)
10/2017 - 07/2005
2Fibrosis (Cirrhosis)
01/2015 - 03/2011
2Skin Diseases (Skin Disease)
02/2014 - 03/2009
2Colitis
05/2013 - 08/2004
2Emphysema
11/2010 - 03/2010

Drug/Important Bio-Agent (IBA)

42CytokinesIBA
01/2021 - 01/2002
311-(2-(dodecyloxy)ethyl)pyrrolidine hydrochloride (DEP)IBA
02/2013 - 04/2002
30Vehicle Emissions (Emissions, Vehicle)IBA
08/2021 - 04/2002
25AllergensIBA
01/2022 - 01/2002
25LipopolysaccharidesIBA
01/2017 - 12/2002
20Particulate MatterIBA
01/2022 - 09/2006
19SandIBA
07/2017 - 11/2005
16ChemokinesIBA
01/2019 - 05/2002
14OvalbuminIBA
01/2016 - 07/2002
14EndotoxinsIBA
02/2011 - 05/2002
13AntigensIBA
01/2014 - 12/2002
12Interleukin-6 (Interleukin 6)IBA
01/2021 - 10/2003
10Immunoglobulin G (IgG)IBA
01/2019 - 01/2002
9Diethylhexyl Phthalate (DEHP)IBA
10/2021 - 08/2006
9Organic Chemicals (Chemicals, Organic)IBA
07/2017 - 11/2004
8Immunoglobulins (Immunoglobulin)IBA
02/2014 - 07/2002
8Proteins (Proteins, Gene)FDA Link
11/2010 - 04/2002
7InterleukinsIBA
01/2021 - 06/2004
7Interleukin-5 (Interleukin 5)IBA
11/2020 - 01/2002
7phthalic acid (phthalate)IBA
07/2017 - 08/2006
7Chemotactic FactorsIBA
02/2013 - 04/2004
7urinastatin (MR 20)IBA
04/2010 - 03/2005
6Immunoglobulin E (IgE)IBA
01/2019 - 01/2002
6MetallothioneinIBA
05/2013 - 01/2005
6Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA
04/2010 - 03/2005
5Biomarkers (Surrogate Marker)IBA
10/2019 - 04/2002
4CarbonIBA
09/2017 - 09/2006
4GlucansIBA
04/2016 - 07/2005
4Interleukin-13IBA
01/2015 - 08/2005
4SootIBA
04/2011 - 09/2006
4Pharmaceutical PreparationsIBA
04/2010 - 03/2005
4Rosmarinic AcidIBA
07/2006 - 04/2003
3Messenger RNA (mRNA)IBA
01/2022 - 01/2019
3Benzo(a)pyreneIBA
12/2021 - 11/2016
3bisphenol AIBA
01/2019 - 01/2016
3PlasticizersIBA
07/2017 - 05/2009
3Environmental Pollutants (Pollutants, Environmental)IBA
07/2017 - 05/2002
3Toll-Like Receptors (Toll-Like Receptor)IBA
01/2017 - 01/2007
3Reactive Oxygen Species (Oxygen Radicals)IBA
03/2014 - 04/2002
3Pancreatic Elastase (Elastase)IBA
04/2011 - 03/2010
3Carbon Nanotubes (Carbon Nanotube)IBA
04/2010 - 12/2008
3Interleukin-1beta (Interleukin 1 beta)IBA
03/2010 - 01/2004
3AntioxidantsIBA
10/2009 - 12/2002
3Vitamin EFDA LinkGeneric
10/2004 - 12/2002
2titanium dioxide (Titania)FDA Link
12/2021 - 03/2009
2Biological ProductsIBA
12/2021 - 11/2010
2CholesterolIBA
01/2021 - 04/2004
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2021 - 07/2003
2Air Pollutants (Pollutants, Air)IBA
01/2021 - 07/2017
2Protease Inhibitors (Protease Inhibitor)IBA
12/2020 - 01/2020
2Silicon Dioxide (Silica)FDA LinkGeneric
08/2019 - 01/2016
2Glucose (Dextrose)FDA LinkGeneric
01/2019 - 03/2014
2Drinking WaterIBA
01/2019 - 08/2004
2EstersIBA
07/2017 - 05/2009
2quinone (benzoquinone)IBA
06/2017 - 01/2005
2ElementsIBA
12/2016 - 04/2016
2LigandsIBA
04/2016 - 03/2011
2LipidsIBA
03/2014 - 12/2012
2diisononyl phthalateIBA
02/2014 - 04/2010
2OzoneIBA
12/2012 - 12/2008
2PeroxiredoxinsIBA
12/2012 - 10/2009
2Therapeutic UsesIBA
06/2012 - 05/2011
2InflammasomesIBA
01/2012 - 10/2010
2Methacholine Chloride (Methacholine)FDA Link
11/2010 - 03/2010
2Cholinergic Agents (Cholinergics)IBA
11/2010 - 03/2010
2Alkaline PhosphataseIBA
11/2010 - 03/2010
2L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
11/2010 - 03/2010

Therapy/Procedure

2Aftercare (After-Treatment)
01/2015 - 12/2008